Skip to main content

imarkRoy J. CarverUniversity of Illinois
Biotechnology Center

Transgenic Mouse Facility
Fuming Pan, Director
505 S. Goodwin Ave.,
15 Morrill Hall, Urbana, IL 61801
Phone: (217) 244-0649     
FAX:  (217) 244-0466    


Transgenic Mouse Production

Transgenic Mouse Production – The facility will generate transgenic mouse by microinjection of foreign DNA into the pronuclei of fertilized mouse eggs.

$5,210 - Campus                 $5,731 -  External
*Plus applicable mouse purchase

Gene Targeting

Gene Targeting – The facility will produce targeted mouse ES cell lines with a targeting construct provided by the investigator.

$6,560  - Campus                 $7,216 -  External      

Knockout Mouse Production

Knockout Mouse Production – Up to 2 targeted ES cells clones will be microinjected into mouse blastocysts to generate chimeras.

$5,340 - Campus                   $5,874 - External      

*Plus applicable mouse purchase.


Embryo Cryopreservation – 8-cell embryos from a mouse line supplied by the investigator will be cryopreserved and stored in liquid nitrogen.

$1,790 - Campus                


Mouse line rederivation – Fertilized oocytes from an infected mouse line will be dissected out and implanted into healthy fosters to carry them to term.

$1,820 - Campus  

*Plus applicable mouse purchase.        

Mouse Embryo Recovery

Mouse Embryo Recovery-frozen mouse embryos will be thawed and surgically transferred to fosters to retrieve mouse lines.

$2,040 - Campus          

*Plus applicable mouse purchase.

Miscellaneous/Consulting Services

TMF will provide assistance in mouse colony breeding and other related techniques.

$40/hour, minimum one hour charge.


Facility users other than State of Illinois institutions are subject to a 28.6% indirect cost rate for federally funded projects . State of Illinois non-Federally funded projects are subject to a 21.9% indirect cost rate.  For off-campus projects exceeding $5,000, a contract must be negotiated through University of Illinois Grants and Contracts.  For further information contact Dr. Mark A. Mikel (217-244-0144; ), Associate Director of the Roy J. Carver Biotechnology Center.


All work performed by the Roy J. Carver Biotechnology Center (CBC) should be acknowledged in scholarly publications, posters, and presentations. Proper recognition allows us to measure the impact of our work and supports our initiatives in obtaining sponsored funding. In addition, any CBC personnel who make a substantial intellectual or experimental contribution are deserving of further recognition as co-author.