Carver Biotech

Author name: Race Tubongbanua

Metabolomics

Quantitative Glucocorticoid Method

New Quantitative Glucocorticoid Method This new quantitative assay includes cortisol, cortisone, corticosterone and 21-deoxycortisol This assay is able to distinguish between corticosterone and 21-deoxycortisol which share the same mass any major fragments If you are interested in this specific assay, select “Custom LC-MS assay with < 5 metabolites” on the sample submission form and specify Glucocorticoid method.  

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CMtO

CMtO Operation Updates

The CMtO will be closed beginning at 5:00 PM on Monday, December 23 and remain closed until Thursday, January 2, 2025 in observance of the UIUC Winter Break.   UIUC 10x Special Event CMtO Operation Updates CMtO Operation Updates • December 23, 2024 The CMtO will be closed beginning at 5:00 PM on Monday, December 23 and remain Read More » CMtO Operation Updates CMtO Operation Updates • November 25, 2024 The CMtO will be closed beginning at 12:00 PM (noon) on Wednesday, November 27 – Read More »

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Functional Genomics

Thermo Fusion Orbitrap Tribrid MassSpectrometer with ETD Fragmentation  

The versatile Fusion Orbitrap Tribrid mass spectrometer accommodates a variety of analysis types. This instrument is used for everything from routine protein identification to post-translational modification identification and localization using one of its three fragmentation mechanisms (CID, HCD,and ETD). Its tribrid design also permits higher order tandem MS scans, meaning that we can make use of newer isobaric reagents such as iTRAQ and TMT for label-based protein quantitation in addition to more traditional methods such as SILAC. The facility also has a Advion TriVersa NanoMate robot to facilitate intact protein analyses using the Fusion.

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Metabolomics

PacBio REVIO (NEW!!)

This is the latest instrument from PacBio, it produces the longest reads with the highest accuracy versus previous PacBio instruments. It is the instrument of choice for assembly of complex genomes, metagenomes, genome resequencing with long reads, full-length 16S and other amplicons and full-length transcriptomes (IsoSeq). One REVIO Cell produces

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DNA Services

The PacBio REVIO is here!

This cutting-edge long-read sequencing instrument offers exciting new capabilities. Its applications span a wide range, including de novo genome assembly for both eukaryotic and prokaryotic species, the most cost-effective genome resequencing using long reads, sequencing of long amplicons including full-length 16S, and full-length mRNA sequencing from bulk or single-cell RNAseq samples. The standout advantage of the REVIO lies in its significantly reduced sequencing cost. Compared to the Sequel, it produces three times the data for the same cost, making it an best choice for researchers for their long-reads needs. We eagerly anticipate discussing how long-read sequencing can enhance your research endeavors. Feel free to reach out for further details! 😊

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DNA Services

Single-Cell and Spatial Transcriptomics

The Single-Cell and Spatial Transcriptomics workshop was a huge success. This workshop included presentations of all the latest applications, technologies, and instrumentation. A recording of all the lectures can be accessed in the link below. If you are considering utilizing single-cell or spatial transcriptomics, please watch the recording to become familiarized with the most up to date information. https://mediaspace.illinois.edu/media/t/1_n3a5pevn

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DNA Services

The NovaSeq X Plus is here!

Chris Wright and Alvaro Hernandez loading the NovaSeq X Plus The NovaSeq X Plus is the latest and most advanced DNA sequencing instrument currently available, able to sequence up to 20 billion DNA fragments in just one day. To translate this to samples, the output is 6 Tb of genomic information, equivalent to 2,000 human genomes, 6,000 soybean genomes, or 1 million bacterial genomes! In addition, The X Plus system reduces current sequencing costs by up to **50%**, further enabling PIs to extend their funding into new or more complex research, utilizing genomics, transcriptomics, epigenomics, single-cell multiomics, spatial transcriptomics and proteomics, and metagenomics at a significantly lower cost compared to any other sequencing technology.

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