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Protein Sciences
Peter Yau, Ph.D - Director
315 Noyes Laboratory,
505 South Mathews Avenue, Urbana, IL 61801
Phone: (217) 333-3841 

Protein Sciences Facility Pricing

Prior to project initiation, a meeting is required with CBC staff to discuss each project. If mutually agreed that the CBC can support the project, we will deliver a quote outlining the approach, timeline, and cost for the agreed service(s). As this is cutting-edge science, we cannot guarantee success, in all cases the user will be billed for cost and labor for CBC effort per our fee structure. After acceptance of the quote, the user will fill out and return the sample submission form provided with the quote, and also found on each CBC facility’s website. All samples are assumed to be safe, and no greater than BSL1, unless otherwise agreed upon in advance. The user must diligently and transparently followed all University of Illinois sample acquisition, movement, and safety protocols.


Prices effective June 1, 2021


Preparative Liquid Chromatography



     Buffer Preparation

     Fraction Collection




Self Service


Typhoon 9400 Imaging (half hour minimum)

$89.00/half hour

Intact Mass Analysis with Advion TriVersa and Fusion
(2 hour minimum, prior training required)


Intact Mass Analysis with Advion TriVersa and UHMR
(2 hour minimum, prior training required)


Enzymatic Digestion


Trypsin (default unless otherwise noted)





LysC + Trypsin sequential digest


Other proteases (chymotrypsin, thermolysin, etc.)

cost of enzyme + $53.00

Additional Proteomic Sample Preparation


Protein Extraction

Reduction & Alkylation


Sample Desalting (StageTip)


Detergent Removal


C18 Column (Sep-Pak)


Buffer Exchange (Spin column)


Phosphorylation Enrichment (Fe-IMAC or TiO2)


Mass Spectrometry


LC-MS/MS (45 min rapid analysis)


LC-MS/MS (60 min standard analysis)


LC-MS/MS (90 min analysis)


LC-MS/MS (120 min extended analysis)


LC-MS/MS (180 min analysis)

In-gel bundle for on-campus projects (CEM digest + rapid LC-MS/MS)


Quantitative Proteomic Analysis


    Isotopic label (iTRAQ, TMT, dimethyl labeling, etc.)

inquire for quote

Intact protein analysis*




5 mL and under


5 mL to 200 mL


Additional Data Analysis


Custom Database or Modification Added to Mascot Server


*Prior consultation recommended

Facility users not within the State of Illinois are subject to a 31.9% indirect cost rate. State of Illinois institutions are subject to a 31.9% indirect cost rate for Federally-funded projects, and 10% indirect cost rate for non-Federally funded projects. Off-campus projects require an off-campus user form, to be provided by the facility, and if over $10,000 a technical testing agreement. For further information contact Dr. Mark A. Mikel (217-244-0144; ), Associate Director of the Roy J. Carver Biotechnology Center.

All scientific work performed by the Roy J. Carver Biotechnology Center (CBC) is required to be acknowledged in scholarly publications, posters, and presentations.  Proper recognition allows us to measure the impact of our work and supports our initiatives in obtaining sponsored funding. In addition, any CBC personnel who make a substantial intellectual or experimental contribution are deserving of further recognition as co-author.