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University of Illinois

Illinois Campus Quad

Metabolomics Core Facility

The Metabolomics Core Facility of the Roy J. Carver Biotechnology Center, University of Illinois Urbana-Champaign identifies and quantifies small molecules (metabolites) from a variety of origins such as biological tissue, blood, serum, plasma, cell, cell medium, urine, feces, among others. We provide support for untargeted and targeted metabolite profiling, detecting such compounds as sugars and sugar phosphates, alcohols, amine and polyamines, amino acids, fatty acids, complex lipids, nucleotides, organic acids, phenolics, bile acids, steroids/hormones, phthalates, PFAS, and many more emerging metabolites. We help execute projects, including protocol development, sample preparation, instrument method development, instrument data acquisition, and data processing.

Multiple complementary analytical methods are utilized with mass spectrometry. Our laboratory possesses several mass spectrometers, including four liquid chromatograph-mass spectrometers such as a Thermo Fisher Q-Exactive hybrid quadrupole-orbitrap, a Thermo Fisher Altis triple quadrupole, Sciex 6500+ triple quadrupole, and a Sciex 5500 hybrid triple quadrupole-ion trap (QTRAP), as well as three gas chromatograph-mass spectrometers such as an Agilent 5977A, Agilent 5975C, and Agilent 5973. We have been primarily funded through the generosity of the Roy J. Carver Charitable Trust and National Center for Research Resources.

Analytical Services

Untargeted Analysis

  • LC-MS assays include metabolite profiling and lipid profiling

  • Data: Semi-quantitative

Targeted Analysis

  • LC-MS and GC-MS assays specific for classes of metabolites or pathways

  • Data: Quantitative or semi-quantitative

Custom Methods

  • Inquire for more information

Additional Information

Please begin by visiting our Services/Pricing page. If interested in analysis, complete a Sample Submission Form and Email it to us at metabolomics@illinois.edu.